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2 edition of assessment of the use of intravenous iron dextran in hemodialysis patients found in the catalog.

assessment of the use of intravenous iron dextran in hemodialysis patients

Jenny Ng

assessment of the use of intravenous iron dextran in hemodialysis patients

by Jenny Ng

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  • 7 Currently reading

Published .
Written in English


Edition Notes

Kingston General Hospital

The Physical Object
Pagination16 leaves
Number of Pages16
ID Numbers
Open LibraryOL19044709M

Alternatively, treatment of IDA in patients requiring erythropoiesis-stimulating agents (ESAs) is more predictably achieved by use of intravenous (i.v.) iron. Unfortunately, the development of serious adverse events (SAEs) from high molecular-weight iron dextran has led to reluctance to use i. v. iron in the treatment of by: Various trials have assessed the safety of FGC in patients receiving hemodialysis without a test dose, in iron dextran–sensitive and iron dextran–tolerant patients, and in patients receiving a dose of mg or more–23 All of the patients in these studies were receiving hemodialysis, and the mean age ranged from 50 to 60 : Patrick Viet-Quoc Nguyen, Judith Latour.

Dr. Jerry Yee is a Nephrologist in Detroit, MI. Find Dr. Yee's phone number, address, insurance information, hospital affiliations and more. Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by Scott Moses, MD, last revised on 5/3/ and last published on 5/3/

Purpose Unresponsiveness to erythropoiesis-stimulating agents, occurring in 30% to 50% of patients, is a major limitation to the treatment of chemotherapy-related anemia. We have prospectively evaluated whether intravenous iron can increase the proportion of patients with chemotherapy-related anemia who respond to darbepoetin. Patients and Methods Between December and February , Cited by:   The limited data suggest that dosing instructions for adults can be used for pediatric patients needing Tranexamic Acid Injection therapy. Geriatric Use. Clinical studies of Tranexamic Acid Injection did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects/


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Assessment of the use of intravenous iron dextran in hemodialysis patients by Jenny Ng Download PDF EPUB FB2

As part of the North American clinical trials for iron sucrose injection, we examined the effect of intravenous (IV) iron sucrose in 23 hemodialysis patients with documented sensitivity to iron.

The recommendation to use IV rather than oral iron in CKD-5D patients was supported by a number of clinical studies in both haemodialysis and peritoneal dialysis patients (although the number of. Iron sucrose and ferric gluconate are non-dextran forms of intravenous iron that appear to be safer than iron dextran with lower risk of anaphylactoid reactions, and a similar rate of serious adverse events when compared to placebo.

Two strategies for administering intravenous iron to. Patients with chronic kidney disease (CKD) often present with iron depletion and iron deficiency anaemia (IDA) because of frequent blood (and iron) loss.

Therapy consists of repletion of iron stores and intravenous (i.v.) iron has become the standard care in this setting. However, older i.v. iron preparations have their by: Hemodialysis patients need iron to replenish ongoing losses. We evaluated the short-term safety and efficacy of infusing soluble ferric pyrophosphate by dialysate.

Maintenance hemodialysis patients receiving erythropoietin were stabilized on regular doses of intravenous (i.v.) iron dextran after oral iron supplements were discontinued.

Purpose Recombinant human erythropoietin (rHuEPO) is the standard of care for patients with chemotherapy-related anemia. Intravenous (IV) iron improves hemoglobin (Hb) response and decreases dosage requirements in patients with anemia of kidney disease, but its effect has not been studied in randomized trials in cancer patients.

Methods This prospective, multicenter, open-label, Cited by: Intravenous iron preparations are typically classified as non-dextran-based or dextran/dextran-based complexes.

The carbohydrate shell for each of these preparations is unique and is key in determining the various physicochemical properties, the metabolic pathway, and the immunogenicity of the iron-carbohydrate complex. As intravenous dextran can cause severe, antibody-mediated dextran-induced Cited by:   While intravenous iron is considered the standard treatment in patients with IBD (with active disease) in Europe, oral iron remains the first-line treatment in the US.

24 Some authors propose intravenous administration as the preferred route for all patients with IBD (e.g.

Gasche and colleagues 25), while other authors point out that both Cited by: 4. The patient was given an ampule of calcium gluconate and an intravenous injection of insulin along with D 50 W.

The patient was subsequently placed on hemodialysis within 2 hours with a low-potassium dialysate to remove potassium. Following hemodialysis, the potassium concentration was meq/L, but 6 hours later the potassium was meq/L.

Background: Iron administration has been implicated as a cause of poor clinical outcome in maintenance hemodialysis (MHD) patients. However, the role of low iron levels in the clinical outcome of MHD patients is not clear. Methods: We examined the predicting value of baseline serum iron level on prospective mortality and hospitalization in a cohort of all 1, MHD patients from 10 DaVita Cited by: Dextran is are multibranched polysaccharides found to bind with proteins.

In this case sephadex we are seeing a brand name for a product made out of this sugar by GE Healthcare. They are used in. John K. Maesaka is a Nephrologist in Mineola, NY. Find Dr. Maesaka's phone number, address, insurance information, hospital affiliations and more. Based on the data presented herein, oral iron therapy should be preferred for patients with mild iron deficiency anemia (Hb ≥ 10 g/dL) in quiescent disease stages unless they are intolerant or have an inadequate response (Hb increase.

Iron concentrations, serum {01} (determinations are recommended when deemed necessary to recognize and prevent hemosiderosis and progressive accumulation of iron in patients with chronic renal failure, {} Hodgkin's disease, or rheumatoid arthritis, or in patients receiving large doses of iron dextran; patients on chronic renal dialysis may.

Patients with chronic kidney disease (CKD) often present with iron depletion and iron deficiency anaemia (IDA) because of frequent blood (and iron) loss.

Therapy consists of repletion of iron stores and intravenous (i.v.) iron has become the standard care in this setting. However, older i.v. iron preparations have their by: Clinical Guidelines for the Use of Parenteral and Enteral Nutrition in Adult and Pediatric Patients JPENIssue 3, pp.

- Nutrition Support Therapy During Adult Anticancer Treatment and in Hematopoietic Cell Transplantation JPENIssue 5, pp. - The nutritional management of pregnant adults with chronic kidney disease (CKD) presents the challenge of combining necessary modifications in nutrient requirements for both pregnancy and kidney impairment.

The dietitian must follow these women closely to ensure adequate intakes of kilocalories, protein, and specific vitamins and by: 6. In the control period (June to May ), patients with iron-deficiency anemia (i.e., TSAT less than 20% and/or ferritin less than μg/L) received iron by the conventional accelerated regimen, with IV iron administered for a total of 8 (sodium ferric gluconate) or 10 (iron dextran) consecutive dialysis sessions, followed by monthly.

Iron status safety thresholds of TSAT >50% or serum ferritin > µg/l were exceeded by 28 out of (%) and 55 out of (%) patients, respectively, 2 weeks after the first administration of study medication (safety population, only patients with non-missing measurements), decreasing to seven out of (%) and 22 out of ( Vol IssueAugust ISSN: X (Print) X (Online) Clinical outcome of pediatric patients on peritoneal dialysis under adequacy control.

Intravenous iron dextran and erythropoietin use in pediatric hemodialysis patients. Fishbane S, Ungureanu V, Maesaka JK, Kaupke CJ, Lim V, Wish J: Safety of intravenous iron dextran in hemodialysis patients. Am J Kidney Dis –, PubMed CrossRef Google Scholar Cited by: 1.Anaphylaxis has been reported in % of patients receiving intravenous iron dextran.

Such reactions can occur even with iron preparation with derivatized dextran ligands or low molecular mass dextran ligands (1,–7, Daltons), although less frequently [7,61].Cited by:   Preoperative use of parenteral iron Correction of iron deficiency is critical in chronic hemodialysis patients, and intravenous administration is superior to the oral route in this goal.

-weight forms of iron dextran45 but nevertheless the European Best Practice Guidelines do not generally recommend use of iron dextran due to the risk.